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Function of alternative splicing

Material type:

TextSeries: ; Gene, 344, p.1-20, 2005Contained works:

Stamm, S
Ben-Ari, S
Rafalska, I
Tang, Y
Zhang, Z
Toiber, D
Thanaraj, T.A
Thanaraj, T.A

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Abstract: Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of human genes. Unlike promoter activity, which primarily regulates the amount of transcripts, alternative splicing changes the structure of transcripts and their encoded proteins. Together with nonsense-mediated decay (NMD), at least 25

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Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of human genes. Unlike promoter activity, which primarily regulates the amount of transcripts, alternative splicing changes the structure of transcripts and their encoded proteins. Together with nonsense-mediated decay (NMD), at least 25

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