02654nam a2200289Ia 4500001001000000003001000010005001700020008004100037020001500078020001800093040000900111082002200120100002500142245007600167250001000243264003800253300004800291504005200339520161900391650001402010700003002024700005502054856009702109942001202206999001502218952013102233000008374MX-MdCICY20260521090513.0071109s2008    nyua   f p    001 0 eng d  a071677108X  a9780716771081  cCICY04a572.3bL4455 20081 aLehninger, Albert L.10aLehninger principles of biochemistry /cDavid L. Nelson, Michael M. Cox  a5 ed.31aNew York :bW.H. Freeman, cc2008  a1 v. (Varias paginaciones) :bil. ;c29 cm.  aIncluye referencias bibliográficas e índice3 aThe first edition of Principies of´Biochemistry, written by Albert Lehninger twenty-ñve years ago, has served as the starting point and the model for our four subsequent editions. Over that quarter-century, the world of biochem-istry has changed enormously. Twenty-ñve years ago, not a single genome had been sequenced, not a single membrane protein had been solved by crystallography, and not a sin¬gle knockout mouse existed. Ribozymes had just been dis-covered, PCR technology introduced, and archaea recognized as members of a kingdom sepárate from bac¬teria. Now, newgenomic sequences are announced weekly, new protein structures even more frequently, and re-searchers have engineered thousands of different knock-out mice, with enormous promise for advances in basic biochemistry, physiology, and medicine. This fifth edition contains the photographs of 31 Nobel laureates who have received their prizes for Chemistry or for Physiology or Med¬icine since that first edition of Principies of Biochemistry. One major challenge of each edition has been to re-flect the torrent of new information without making the book overwhelming for students having their first en-counter with biochemistry. This has required much care-ful sifting aimed at emphasizing principies while still conveying the excitement of current research and its promise for the future. The cover of this new edition ex-emplifies this excitement and promise: in the x-ray struc-ture of RNA polymerase, we see DNA, RNA, and protein in their informational roles, in atomic dimensions, caught in the central act of information transfer14aBIOQUMICA12aCox, Michael M., ecoaut.12aNelson, David L., q(David Lee), d1942-, ecoaut.40uhttps://www.cicy.mx/sitios/sib/doctoelectronico/8374.pdfzVer tabla de contenido y/o resumen  2ddccBK  c7666d7666  00102ddc40708CGaCICYbCICYcCLd2024-10-09l3m2o572.3 L4455 2008p8259r2026-01-28 11:17:16s2026-01-28w2024-10-09yBK