03251nam a22004455i 4500001001800000003000900018005001700027007001500044008004100059020001800100020001900118024003500137082001700172100003000189245012100219264004600340300003200386336002600418337002600444338003600470347002400506505089700530520089001427650001402317650001402331650001602345650001702361650002102378650001402399650002902413700002702442710003402469773002002503776003602523856010102559912001402660942001202674999001702686952010202703978-0-387-93874-5DE-He21320260521092022.0cr nn 008mamaa100301s2010    xxu|    s    |||| 0|eng d  a9780387938745  a997803879387457 a10.1007/978-0-387-93874-52doi04a614.59992231 aRosenthal, Eben.eeditor.10aOptical Imaging of Cancerh[electronic resource] :bClinical Applications /cedited by Eben Rosenthal, Kurt R. Zinn. 1aNew York, NY :bSpringer New York,c2010.  aXIII, 272bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aI: Optical Imaging Principles -- Optical Imaging of Cancer: Enhancing Detection and Resection -- Endoscopic Techniques for Optical Imaging -- Design and Use of the Surgical Microscope in Fluorescence-Guided Surgery -- Fluorophores for Optical Imaging -- II: Cancer Targeting Strategies -- Overview of Cancer Detection and Monitoring Strategies -- The Application of Tissue Autofluorescence in Detection and Management of Oral Cancer and Premalignant Lesions -- Proteinase Optical Imaging Tools for Cancer Detection and Response to Therapy -- Illustrating Molecular Events with Light: A Perspective on Optical Reporter Genes -- III: Preclinical and Clinical Investigations -- Optical Imaging of Primary Tumors -- Nodal Staging of Cancer Using Diagnostic Optical Imaging Techniques -- Optical Coherence Tomography for Cancer Detection -- Optical Imaging of Cancer: Neuro-oncologic Applications.  aOptical detection represents the next great horizon for cancer imaging. As molecularly targeted therapeutic agents are delivered to the clinic in increasing numbers, there is a parallel opportunity to advance optical imaging techniques. Because of its limited toxicity and potential for real-time information, optical imaging represents an underdeveloped modality in clinical medicine. Optical Imaging of Cancer: Clinical Applications explores the preclinical and clinical data to support the use of these techniques in cancer imaging. Different fluorescent delivery modalities are explored: from monoclonal antibodies to viral vector delivery. Indications for use include monitoring therapuetic delivery, early detection, and operative removal techniques in all stages of clinical development. This book represents the best and most clinically relevant techniques currently available. 0aMEDICINE. 0aONCOLOGY. 0aTOXICOLOGY.14aBIOMEDICINE.24aCANCER RESEARCH.24aONCOLOGY.24aPHARMACOLOGY/TOXICOLOGY.1 aZinn, Kurt R.eeditor.2 aSpringerLink (Online service)0 tSpringer eBooks08iPrinted edition:z978038793873840uhttp://dx.doi.org/10.1007/978-0-387-93874-5zVer el texto completo en las instalaciones del CICY  aZDB-2-SBL  2ddccER  c35481d35481  00102ddc40708LEaCICYbCICYcELd2025-10-06l0o614.5999r2025-10-06 08:44:32w2025-10-06yER