03251nam a22004335i 4500001001800000003000900018005001700027007001500044008004100059020001800100020001900118024003500137040000900172082001400181100003100195245012100226264004600347300003400393336002600427337002600453338003900479347002400518490006900542505069500611520111301306650001402419650001402433650001602447650001902463650001702482650001902499650002102518650001602539710003402555773002002589776003602609830006902645856010302714978-0-387-70956-7DE-He21320260521091934.0cr nn 008mamaa100301s2007    xxu|    s    |||| 0|eng d  a9780387709567  a997803877095677 a10.1007/978-0-387-70956-72doi  cCICY04a612.82231 aPasterkamp, R. J.eeditor.10aSemaphorins: Receptor and Intracellular Signaling Mechanismsh[recurso electrónico] /cedited by R. J. Pasterkamp. 1aNew York, NY :bSpringer New York,c2007.  aXIV, 147 p.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  arecurso en líneabcr2rdacarrier  atext filebPDF2rda1 aAdvances in Experimental Medicine and Biology,x0065-2598 ;v6000 aThe CRMP Family of Proteins and Their Role in Sema3A Signaling -- GTPases in Semaphorin Signaling -- Intracellular Kinases in Semaphorin Signaling -- MICAL Flavoprotein Monooxygenases: Structure, Function and Role in Semaphorin Signaling -- Signaling of Secreted Semaphorins in Growth Cone Steering -- Modulation of Semaphorin Signaling by Ig Superfamily Cell Adhesion Molecules -- Proteoglycans as Modulators of Axon Guidance Cue Function -- Semaphorin Signals in Cell Adhesion and Cell Migration: Functional Role and Molecular Mechanisms -- Semaphorin Signaling During Cardiac Development -- Semaphorin Signaling in Vascular and Tumor Biology -- Semaphorin Signaling in the Immune System.  aThe book summarizes our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins. Originally these protein were identified as "axon guidance cues" important for the formation of nerve tracts but now it is realized that semaphorins subserve several distinct functions in a multitude of organ systems. The purpose of this book is to summarize our knowledge and make it available as a useful and comprehensive tool for the scientific community. This book will both be interesting for people working in the field as well as colleagues that work in other fields of science and would like to learn more about semaphorins and associated signaling mechanisms. All the latest techniques and results are summarized in this book which covers the entire semaphorin field from neurosciences to cardiovascular research and beyond. The strength of this book is that it gives a very comprehensive overview of all our knowledge of semaphorin biology and signaling and allows one to compare semaphorin functions between different biological systems. 0aMEDICINE. 0aONCOLOGY. 0aIMMUNOLOGY. 0aNEUROSCIENCES.14aBIOMEDICINE.24aNEUROSCIENCES.24aCANCER RESEARCH.24aIMMUNOLOGY.2 aSpringerLink (Online service)0 tSpringer eBooks08iPrinted edition:z9780387709550 0aAdvances in Experimental Medicine and Biology,x0065-2598 ;v60040uhttp://dx.doi.org/10.1007/978-0-387-70956-7zVer el texto completo en las instalaciones del CICY