03360nam a22003615i 4500001001800000003000900018005001700027007001500044008004100059020001800100020001900118024003500137040000900172082001400181100002700195245009900222264003800321300003300359336002600392337002600418338003900444347002400483505081100507520141801318650001402736650001902750650001702769650001902786710003402805773002002839776003602859856010302895978-0-387-68561-8DE-He21320260521091928.0cr nn 008mamaa100301s2007    xxu|    s    |||| 0|eng d  a9780387685618  a997803876856187 a10.1007/978-0-387-68561-82doi  cCICY04a612.82231 aCurtis, Ivan.eeditor.10aIntracellular Mechanisms for Neuritogenesish[recurso electrónico] /cedited by Ivan Curtis. 1aBoston, MA :bSpringer US,c2007.  aXV, 333 p.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  arecurso en líneabcr2rdacarrier  atext filebPDF2rda0 aAdhesion-Induced Intracellular Mechanisms of Neurite Elongation -- Regulation of Growth Cone Initiation and Actin Dynamics by ADF/Cofilin -- Role of Microtubules and MAPs During Neuritogenesis -- Small GTPases: Mechanisms Linking Membrane Traffic to Cytoskeleton During Neuritogenesis -- Exocytic Mechanisms for Axonal and Dendritic Growth -- Role of the Golgi Apparatus During Axon Formation -- Focal Adhesion Kinase in Neuritogenesis -- Regulation of Neuronal Morphogenesis by Abl Family Kinases -- Membrane Glycolipids in Neurotrophin Receptor-Mediated Signaling -- Wnt Signaling in Neurite Development -- Role of CRMP-2 in Neuronal Polarization -- Regulation of Axon Branching -- Comparative Analysis of Neural Crest Cell and Axonal Growth Cone Dynamics and Behavior -- Mechanisms of Axon Regeneration.  aA major issue of modern neurobiology is to understand how neurons extend their neurites to form a functional network. While a large amount of information is available on the extracellular mechanisms driving neuritogenesis, the study of the intricate molecular machinery underlying the intracellular mechanisms has only recently been addressed. The purpose of this book is to present novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction. In particular, the proposed authors would address the importance of the integration among distinct aspects of the cell biology of developing neurons involved in neurite extension. The aim of the book is to present this topic to the general readership of neurobiologists and molecular and cellular biologists to further stimulate the interest into this exciting section of neurobiology. Moreover, the book could represent a reference for researchers directly involved in the study of neuronal development, and a textbook for PhD courses in molecular neurobiology The authors contributing to this book are all internationally recognized leaders in their respective fields of research, and the work from their laboratories embodies state of the art approaches to address this fundamental aspect of molecular neurobiology. 0aMEDICINE. 0aNEUROSCIENCES.14aBIOMEDICINE.24aNEUROSCIENCES.2 aSpringerLink (Online service)0 tSpringer eBooks08iPrinted edition:z978038733128740uhttp://dx.doi.org/10.1007/978-0-387-68561-8zVer el texto completo en las instalaciones del CICY