01357nam a2200277Ia 4500003001000000005001700010040000900027245009500036490008000131520047600211650001300687650001100700650001700711650000700728650001100735650002800746700001600774700001200790700001900802700001600821700001800837700001300855700001400868856015600882008004101038MX-MdCICY20260521091737.0  cCICY10aA validated 1H NMR method for the determination of the degree of deacetylation of chitosan0 vJournal of Pharmaceutical and Biomedical Analysis, 32(6), p.1149-1158, 20033 aA method for the determination of the degree of deacetylation (DDA)of chitosan by 1H NMR spectroscopy has been formally validated. Chitosans with DDA ranging from 48 to 100 percent have been used for the validation. The method is found to be simple, rapid and more precise than other known techniques like IR or titration for percentDDA measurements. The precision, ruggedness, robustness, specificity, stability and accuracy of the technique are discussed in this paper.14aCHITOSAN14aCHITIN14aPH-SENSITIVE14aIR14a1H NMR14aDEGREE OF DEACETYLATION12aLavertu, M.12aXia, Z.12aSerreqi, A. N.12aBerrada, M.12aRodrigues, A.12aWang, D.12aGupta, A.40uhttps://drive.google.com/file/d/1Hx3yRGU3DkqkfjyQms4HxrE23NyeNre7/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d