01897nam a2200289Ia 4500 MX-MdCICY 20260521091736.0 CICY B-20548 Advances in DNA methylation and demethylation in medicinal plants: a review Molecular Biology Reports, 50(9), p.7783-7796, 2023 DNA methylation and demethylation are widely acknowledged epigenetic phenomena which can cause heritable and phenotypic changes in functional genes without changing the DNA sequence. They can thus affect phenotype formation in medicinal plants. However, a comprehensive review of the literature summarizing current research trends in this field is lacking. Thus, this review aims to provide an up-to-date summary of current methods for the detection of 5-mC DNA methylation, identification and analysis of DNA methyltransferases and demethyltransferases, and regulation of DNA methylation in medicinal plants. The data showed that polyploidy and environmental changes can affect DNA methylation levels in medicinal plants. Changes in DNA methylation can thus regulate plant morphogenesis, growth and development, and formation of secondary metabolites. Future research is required to explore the mechanisms by which DNA methylation regulates the accumulation of secondary metabolites in medicinal plants. DNA DEMETHYLASES DNA METHYLATION DNA METHYLTRANSFERASES MEDICINAL PLANTS SECONDARY METABOLITES Zang, Y. Xie, L. Su, J. Luo, Z. Jia, X. Ma, X. https://drive.google.com/file/d/1ucn7WWCDYX_VUoLtoZcbUqz7CeGfPaf0/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 30576 30576 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-20548 2025-06-25 16:24:51 2025-06-25 REF1