01818nam a2200253Ia 4500003001000000005001700010040000900027245008000036490005600116520100900172650002101181650002001202650002701222650002101249650002601270700001301296700001201309700001101321700001201332700001201344700001101356856015601367008004101523MX-MdCICY20260521091736.0  cCICY10aAdvances in DNA methylation and demethylation in medicinal plants: a review0 vMolecular Biology Reports, 50(9), p.7783-7796, 20233 aDNA methylation and demethylation are widely acknowledged epigenetic phenomena which can cause heritable and phenotypic changes in functional genes without changing the DNA sequence. They can thus affect phenotype formation in medicinal plants. However, a comprehensive review of the literature summarizing current research trends in this field is lacking. Thus, this review aims to provide an up-to-date summary of current methods for the detection of 5-mC DNA methylation, identification and analysis of DNA methyltransferases and demethyltransferases, and regulation of DNA methylation in medicinal plants. The data showed that polyploidy and environmental changes can affect DNA methylation levels in medicinal plants. Changes in DNA methylation can thus regulate plant morphogenesis, growth and development, and formation of secondary metabolites. Future research is required to explore the mechanisms by which DNA methylation regulates the accumulation of secondary metabolites in medicinal plants.14aDNA DEMETHYLASES14aDNA METHYLATION14aDNA METHYLTRANSFERASES14aMEDICINAL PLANTS14aSECONDARY METABOLITES12aZang, Y.12aXie, L.12aSu, J.12aLuo, Z.12aJia, X.12aMa, X.40uhttps://drive.google.com/file/d/1ucn7WWCDYX_VUoLtoZcbUqz7CeGfPaf0/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d