02147nam a2200289Ia 4500003001000000005001700010040000900027090001200036245009400048490004700142520111000189650001501299650002101314650001901335650001601354650002001370700002701390700002801417700003001445700002401475700002701499856015601526942001401682008004101696999001701737952010301754MX-MdCICY20260521091733.0  cCICY  aB-2045810aCasearia essential oil: an updated review on the chemistry and pharmacological activities0 vChemistry & BioDiversity, e202300492, 20233 aCasearia species are found in the America, Africa, Asia, and Australia and present pharmacological activities, besides their traditional uses. Here, we reviewed the chemical composition, content, pharmacological activities, and toxicity of the essential oils (EOs)from Casearia species. The EO physical parameters and leaf botanical characteristics were also described. The bioactivities of the EOs from the leaves and their components include cytotoxicity, anti-inflammatory, antiulcer, antimicrobial, antidiabetic, antioxidant, antifungal, and antiviral activities. The main components associated with these activities are the ?-zingiberene, (E)-caryophyllene, germacrene D, bicyclogermacrene, spathulenol, ?-humulene, ?-acoradiene, and ?-cadinene. Data on the toxicity of these EOs are scarce in the literature. Casearia sylvestris Sw. is the most studied species, presenting more significant pharmacological potential. The chemical variability of EOs components was also investigated for this species. Caseria EOs have relevant pharmacological potential and must be further investigated and exploited.14aSALICACEAE14aNATURAL PRODUCTS14aPHYTOCHEMISTRY14aVAR. LINGUA14aVAR. SYLVESTRIS12aAlexandre Carvalho, F.12aValadares De Moraes, N.12aEduardo Miller Crotti, A.12aJosé Crevelin, E.12aGonzaga Dos Santos, A.40uhttps://drive.google.com/file/d/1CjqGGljqKjJEguL74FOaBiyrIiUTIYhb/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx  2LoccREF1250602s9999    xx |||||s2   |||| ||und|d  c30489d30489  00102Loc40708F1aCICYbCICYcREd2025-06-25l0oB-20458r2025-06-25 16:24:49w2025-06-25yREF1