01529nam a2200217Ia 4500003001000000005001700010040000900027245004600036490007800082520079400160650002300954650001800977650001300995650002101008650003701029650002601066700001101092700001101103856015601114008004101270MX-MdCICY20260521091725.0  cCICY10aChemical synthesis of saponins: An update0 vAdvances in Carbohydrate Chemistry and BioChemistry,  79(1), p.1-62, 20213 aSaponins, as secondary metabolites in terrestrial plants and marine invertebrate, constitute one of the largest families of natural products. The long history of folk medicinal applications of saponins makes them attractive candidates for innovative drug design and development. Chemical synthesis has become a practical alternative to the availability of the natural saponins and their modified analogs, so as to facilitate SAR studies and the discovery of optimal structures for clinical applications. The recent achievements in the synthesis of these complex saponins reflect the advancements of both steroid/triterpene chemistry and carbohydrate chemistry. This chapter provides an updated review on the chemical synthesis of natural saponins, covering the literature from 2014 to 202014aCHEMICAL SYNTHESIS14aGLYCOSYLATION14aSAPONINS14aSTEROID SAPONINS14aSTRUCTURE-ACTIVITY RELATIONSHIPS14aTRITERPENOID SAPONINS12aXu, P.12aYu, B.40uhttps://drive.google.com/file/d/1OJuOMvTa0zX4O16cwahKsmdhJ6OpVoXB/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d