02297nam a2200241Ia 4500003001000000005001700010040000900027245015800036490005600194520137300250650002001623650002901643650002401672700002901696700001901725700003001744700001401774700002201788700001701810700003101827856015601858008004102014MX-MdCICY20260521091712.0  cCICY10aPhenolic compounds and antioxidant activity of Lippia graveolens Kunth residual leaves fermented by two filamentous fungal strains in solid-state process0 vFood and Bioproducts Processing, 136, p.24-35, 20223 aThe residual leaves from essential oil extraction from Mexican oregano (Lippia graveolens)have a potential as a source of bioactive molecules (e.x. flavonoids)that could be extracted by solid state fermentation (SSF)process. In this study, the residual leaves were subjected to a SSF (120 h)by two microorganism Trichoderma harzianum and Rhizopus oryzae evaluating the phenolic compounds (Total polyphenols and flavonoids), the antioxidant activity (DPPH? / FRAP), the bioactivities (?-amylase inhibition and antimicrobial against Escherichia coli), the cytotoxic effect (erythrocytes)and a characterization (HPLC-MS). The results showed that the total polyphenols for T.harzarium did not show statistical differences (first 48 h), and R. oryzae fermentation obtained a higher context (48 h). Also, the higher flavonoid release was present at 48 and 96 h (T. harzianum and R. oryzae). The antioxidant activity decreased in the last fermentation hours, the a-amylase reported a higher inhibition value (29.97 ± 1.97 percent)and antimicrobial capacities; R. oryzae (96 h)did not register a cytotoxic effect. The characterization determined the presence of valuable molecules as ferulic acid 4-O-glucoside, phloridzin and luteolin. The fermentation allowed the recovery of bioactive phenolic compounds that could be an alternative for the revalorization of oregano waste14aMEXICAN OREGANO14aSOLID-STATE FERMENTATION14aBIOACTIVE COMPOUNDS12aBautista-Hernández, I.12aAguilar, C. N.12aMartínez-Ávila, G. C.12aIlina, A.12aTorres-León, C.12aVerma, D. K.12aChávez-González, M. L.40uhttps://drive.google.com/file/d/1iivs68ibsbGGdyHqEGTd3PhUaym8p5Dn/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d