02288nam a2200277Ia 4500 MX-MdCICY 20260521091644.0 CICY B-18864 The GH3 amidosynthetases family and their role in metabolic crosstalk modulation of plant signaling compounds PhytoChemistry, 194, p.113039, 2022 The Gretchen Hagen 3 (GH3)genes encoding proteins belonging to the ANL superfamily are widespread in the plant kingdom. The ANL superfamily consists of three groups of adenylating enzymes: aryl- and acyl-CoA synthetases, firefly luciferase, and amino acid-activating adenylation domains of the nonribosomal peptide synthetases (NRPS). GH3s are cytosolic, acidic amidosynthetases of the firefly luciferase group that conjugate auxins, jasmonates, and benzoate derivatives to a wide group of amino acids. In contrast to auxins, which amide conjugates mainly serve as a storage pool of inactive phytohormone or are involved in the hormone degradation process, conjugation of jasmonic acid (JA)results in biologically active phytohormone jasmonyl-isoleucine (JA-Ile). Moreover, GH3s modulate salicylic acid (SA)concentration by conjugation of its precursor, isochorismate. GH3s, as regulators of the phytohormone level, are crucial for normal plant development as well as plant defense response to different abiotic and biotic stress factors. Surprisingly, recent studies indicate that FIN219/JAR1/GH3.11, one of the GH3 proteins, may act not only as an enzyme but is also able to interact with tau-class glutathione S-transferase (GSTU)and constitutive photomorphogenic 1 (COP1)proteins and regulate light and stress signaling pathways. The aim of this work is to summarize our current knowledge of the GH3 family. GH3 AMIDE CONJUGATES AUXIN JASMONATE SALICYLIC ACID PHYTOHORMONES Wojtaczka, P. Ciarkowska, A. Starzynska, E. Ostrowski, M. https://drive.google.com/file/d/15mdXfJDWZ2pQ6k8Vy4tIJWew_dcmaKv-/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 28946 28946 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-18864 2025-06-25 16:24:20 2025-06-25 REF1