01919nam a2200313Ia 4500003001000000005001700010040000900027090001200036245011200048490004300160520083400203650004001037650003501077650002301112650002101135650002901156700001301185700001201198700001301210700001301223700001201236700001201248700001401260856015601274942001401430008004101444999001701485952010301502MX-MdCICY20260521091626.0  cCICY  aB-1830910aA pair of epimeric cassane-type diterpenoids and a new labdane-type derivative from Caesalpinia decapetala.0 vTetrahedron, 74(28), p.3852-3857, 20183 aCaesaldecins A and B (1a/1b), a pair of epimeric cassane-type diterpenoids containing an ether linkage between C-6 and C-20 and an ?,?-butenolide ring in the northern hemisphere, were isolated from the leaves of the medicinal plant Caesalpinia decapetala (Roth)Alston, along with a new labdane-type diterpenoid, termed as 8(17),11(Z),13(E)-trien-15,18-dioic acid (2). Structures of 1 and 2 were established by extensive spectroscopic analyses, including HRESIMS, 1D and 2D NMR, and electronic circular dichroism (ECD)calculations. The in vitro antibacterial and inhibitory activities against a panel of bacteria and cancer cell lines were evaluated, respectively. Compound 2 displayed moderate antibacterial activity against the methicillin-resistant Staphylococcus aureus subsp. aureus (MRSA)with an MIC50 value of 5.99??g?mL?1.14aCAESALPINIA DECAPETALA (ROTH)ALSTON14aCASSANE-TYPE FURANODITERPENOID14aMIXTURE OF EPIMERS14aECD CALCULATIONS14aANTIBACTERIAL ACTIVITIES12aQiao, Y.12aLiu, Y.12aDuan, X.12aChen, C.12aLiu, J.12aZhu, H.12aZhang, Y.40uhttps://drive.google.com/file/d/19OBytp3ur4XjTtIfCEQTqISf0PUqLxwB/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx  2LoccREF1250602s9999    xx |||||s2   |||| ||und|d  c28400d28400  00102Loc40708F1aCICYbCICYcREd2025-06-25l0oB-18309r2025-06-25 16:02:27w2025-06-25yREF1