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  <titleInfo>
    <title>A pair of epimeric cassane-type diterpenoids and a new labdane-type derivative from Caesalpinia decapetala</title>
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  <name type="personal">
    <namePart>Qiao, Y.</namePart>
  </name>
  <name type="personal">
    <namePart>Liu, Y.</namePart>
  </name>
  <name type="personal">
    <namePart>Duan, X.</namePart>
  </name>
  <name type="personal">
    <namePart>Chen, C.</namePart>
  </name>
  <name type="personal">
    <namePart>Liu, J.</namePart>
  </name>
  <name type="personal">
    <namePart>Zhu, H.</namePart>
  </name>
  <name type="personal">
    <namePart>Zhang, Y.</namePart>
  </name>
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  <abstract>Caesaldecins A and B (1a/1b), a pair of epimeric cassane-type diterpenoids containing an ether linkage between C-6 and C-20 and an ?,?-butenolide ring in the northern hemisphere, were isolated from the leaves of the medicinal plant Caesalpinia decapetala (Roth)Alston, along with a new labdane-type diterpenoid, termed as 8(17),11(Z),13(E)-trien-15,18-dioic acid (2). Structures of 1 and 2 were established by extensive spectroscopic analyses, including HRESIMS, 1D and 2D NMR, and electronic circular dichroism (ECD)calculations. The in vitro antibacterial and inhibitory activities against a panel of bacteria and cancer cell lines were evaluated, respectively. Compound 2 displayed moderate antibacterial activity against the methicillin-resistant Staphylococcus aureus subsp. aureus (MRSA)with an MIC50 value of 5.99??g?mL?1.</abstract>
  <subject>
    <topic>CAESALPINIA DECAPETALA (ROTH)ALSTON</topic>
  </subject>
  <subject>
    <topic>CASSANE-TYPE FURANODITERPENOID</topic>
  </subject>
  <subject>
    <topic>MIXTURE OF EPIMERS</topic>
  </subject>
  <subject>
    <topic>ECD CALCULATIONS</topic>
  </subject>
  <subject>
    <topic>ANTIBACTERIAL ACTIVITIES</topic>
  </subject>
  <relatedItem type="series">
    <titleInfo>
      <title>Tetrahedron, 74(28), p.3852-3857, 2018</title>
    </titleInfo>
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  <identifier type="uri">https://drive.google.com/file/d/19OBytp3ur4XjTtIfCEQTqISf0PUqLxwB/view?usp=drivesdk</identifier>
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