01325nam a2200265Ia 4500003001000000005001700010040000900027245007300036490005500109520050000164650002300664650002400687650001400711650001900725650001700744700001400761700001200775700001600787700001500803700001600818700001300834700001500847856015600862008004101018MX-MdCICY20260521091626.0  cCICY10aCytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan.0 vChinese Chemical Letters, 28(8), p.1711-1715, 20173 aPhytochemical investigation on the seeds of Caesalpinia sappan led to the isolation of five new cassane-type diterpenoids, named 11-oxo-phanginin A (1), caesalsappanins O-Q (2-4)and phanginin U (5), together with five known compounds. The structures of the new compounds were elucidated by extensive analysis of mass spectrometric and 1D and 2D NMR spectroscopic data. All the new compounds showed moderate cytotoxic effects on human breast cancer MCF-7 and human colon cancer HCT116 cell lines.14aCAESALPINIA SAPPAN14aCASSANE DITERPENOID14aPHANGININ14aCAESALSAPPANIN14aCYTOTOXICITY12aWu, Z. F.12aBao, H.12aZhou, F. Y.12aLiu, J. X.12aMeng, F. C.12aFeng, L.12aLin, L. G.40uhttps://drive.google.com/file/d/1aV4mQF6cHvXnJLpA1nF4xYTukE4LyuN4/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d