01564nam a2200313Ia 4500 MX-MdCICY 20260521091617.0 CICY B-18040 Bioactive luteoloside produced by Myroides odoratimimus, solvent-tolerant bacterium form the rhizosphere of Lonicera japonica. Natural Product Research, 33(24), p.3559-3562, 2019 Luteoloside (luteolin-7-O-glucoside), the biomarker of Lonicera japonica, was efficiently bio-synthetized from its cheaper precursor luteolin. The structure of luteoloside was characterized by LC-MS and NMR analyses. Compared to the significant inhibitory effect of luteolin on human hepatocyte cell line LO2 at high doses, luteoloside did not show obvious cytotoxic effects at any test dose. Moreover, luteoloside exhibited obvious promotive effects on human hepatocyte cells, suggesting a potential application in hepatoprotective therapies. MYROIDES ODORATIMIMUS RHIZOSPHERE BACTERIA LONICERA JAPÓNICA BIOTRANSFORMATION LUTEOLOSIDE HEPATOCYTOTOXICITY Zhao, Y. X. Wang, J. J. Zhang, L. Zhang, S. Su, S. L. Duan, J. A. Xu, S. K. https://drive.google.com/file/d/12wsGd1ADosUXcGDJoyoCnwpsEG_PNKfy/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 28138 28138 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-18040 2025-06-25 16:02:22 2025-06-25 REF1