01486nam a2200277Ia 4500003001000000005001700010040000900027245013100036490005600167520054800223650002600771650002500797650002400822650002200846650001600868650002300884700001600907700001600923700001400939700001400953700001400967700001600981700001400997856015601011008004101167MX-MdCICY20260521091617.0  cCICY10aBioactive luteoloside produced by Myroides odoratimimus, solvent-tolerant bacterium form the rhizosphere of Lonicera japonica.0 vNatural Product Research, 33(24), p.3559-3562, 20193 aLuteoloside (luteolin-7-O-glucoside), the biomarker of Lonicera japonica, was efficiently bio-synthetized from its cheaper precursor luteolin. The structure of luteoloside was characterized by LC-MS and NMR analyses. Compared to the significant inhibitory effect of luteolin on human hepatocyte cell line LO2 at high doses, luteoloside did not show obvious cytotoxic effects at any test dose. Moreover, luteoloside exhibited obvious promotive effects on human hepatocyte cells, suggesting a potential application in hepatoprotective therapies.14aMYROIDES ODORATIMIMUS14aRHIZOSPHERE BACTERIA14aLONICERA JAPÓNICA14aBIOTRANSFORMATION14aLUTEOLOSIDE14aHEPATOCYTOTOXICITY12aZhao, Y. X.12aWang, J. J.12aZhang, L.12aZhang, S.12aSu, S. L.12aDuan, J. A.12aXu, S. K.40uhttps://drive.google.com/file/d/12wsGd1ADosUXcGDJoyoCnwpsEG_PNKfy/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d