01212nam a2200265Ia 4500 MX-MdCICY 20260521091617.0 CICY B-18036 Synthesis and biological evaluation of C-13, C-14 modified taxane analogues from 1-deoxybaccatin VI. Natural Product Research, 33(24), p.3478-3484, 2019 our C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group on C-14 could improve the cytotoxic activities. 1-DEOXYBACCATIN VI TAXANE CYTOTOXICITY OXIDATION SYNTHESIS Tang, P. Lin, H. X. Yuan, T. H. Cui, Y. M. https://drive.google.com/file/d/13_-dOfCiQFwRqElhG1uxktUxkLUAN_6H/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 28134 28134 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-18036 2025-06-25 16:02:22 2025-06-25 REF1