01891nam a2200313Ia 4500 MX-MdCICY 20260521091400.0 CICY B-13796 Mechanical and histological evaluation of a PMMA-based bone cement modified with g-methacryloxypropyltrimethoxysilane and calcium acetate BioMaterials, 27(21), p.3897-3903, 2006 Polymethylmethacrylate (PMMA)bone cement is widely used for prosthetic fixation in orthopaedic surgery; however, the interface between bone and cement is a weak zone. We developed a bioactive PMMA cement through modification with g-methacryloxypropyltrimethoxysilane (MPS)and calcium acetate. The purpose of this study was to compare the handling, mechanical and histological properties of the modified bone cement with those of the conventional cement. The modified specimens exhibited higher bonding strength between bone and implant. Histological observation and micro-focus X-ray computed tomogram (micro-CT)images showed that the modified cement exhibited osteoconduction, which the conventional PMMA bone cement lacked. The modification was found to be effective in enabling osteoconduction with PMMA bone cement, thus providing stable fixation for a long period after implantation. BIOACTIVITY BONE CEMENT MECHANICAL PROPERTY IN VITRO TEST IN VIVO TEST Tsukeoka, T. Suzuki, M. Ohtsuki, C. Sugino, A. Tsuneizumi, Y. Miyagi, J. Kuramoto, K. Kuramoto, K. https://drive.google.com/file/d/1uagPc_1moSVqQebXyXO4FYptstkViJeX/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 23933 23933 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-13796 2025-06-25 15:39:29 2025-06-25 REF1