01431nam a2200301Ia 4500003001000000005001700010040000900027090001200036245010300048490006000151520039700211650002600608650000800634650001800642650001800660650002200678650003100700650001500731700001400746700001200760700001300772700001300785856015600798942001400954008004100968999001701009952010301026MX-MdCICY20260521091258.0  cCICY  aB-1186710aApplication of Polyhydroxyalkanoates Nanoparticles as Intracellular Sustained Drug-Release Vectors0 vJournal of BioMaterials Science, 21(1), p.127-140, 20103 aPolyhydroxybutyrate (PHB), co-polyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx), and polylactic acid (PLA)were used to prepare nanoparticles with average sizes of 160, 250 and 150 nm, respectively. A lipid-soluble colorant, rhodamine B isothiocyanate (RBITC), was employed to study drug-release behaviors from these nanoparticles. A high RBITC drug-loading efficiency of over 7514aPOLYHYDROXYALKANOATES14aPHB14aNANOPARTICLES14aDRUG DELIVERY14aSUSTAINED RELEASE14aINTRACELLULAR DRUG RELEASE14aMACROPHAGE12aXiong, Y.12aYao, Y.12aZhan, X.12aChen, G.40uhttps://drive.google.com/file/d/1LKKTUd1lOS3jOqgDaPekJ7bWn-2uXCYZ/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx  2LoccREF1250602s9999    xx |||||s2   |||| ||und|d  c22021d22021  00102Loc40708F1aCICYbCICYcREd2025-06-25l0oB-11867r2025-06-25 14:06:59w2025-06-25yREF1