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  <titleInfo>
    <title>Application of Polyhydroxyalkanoates Nanoparticles as Intracellular Sustained Drug-Release Vectors</title>
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  <name type="personal">
    <namePart>Xiong, Y.</namePart>
  </name>
  <name type="personal">
    <namePart>Yao, Y.</namePart>
  </name>
  <name type="personal">
    <namePart>Zhan, X.</namePart>
  </name>
  <name type="personal">
    <namePart>Chen, G.</namePart>
  </name>
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  <abstract>Polyhydroxybutyrate (PHB), co-polyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx), and polylactic acid (PLA)were used to prepare nanoparticles with average sizes of 160, 250 and 150 nm, respectively. A lipid-soluble colorant, rhodamine B isothiocyanate (RBITC), was employed to study drug-release behaviors from these nanoparticles. A high RBITC drug-loading efficiency of over 75</abstract>
  <subject>
    <topic>POLYHYDROXYALKANOATES</topic>
  </subject>
  <subject>
    <topic>PHB</topic>
  </subject>
  <subject>
    <topic>NANOPARTICLES</topic>
  </subject>
  <subject>
    <topic>DRUG DELIVERY</topic>
  </subject>
  <subject>
    <topic>SUSTAINED RELEASE</topic>
  </subject>
  <subject>
    <topic>INTRACELLULAR DRUG RELEASE</topic>
  </subject>
  <subject>
    <topic>MACROPHAGE</topic>
  </subject>
  <relatedItem type="series">
    <titleInfo>
      <title>Journal of BioMaterials Science, 21(1), p.127-140, 2010</title>
    </titleInfo>
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  <identifier type="uri">https://drive.google.com/file/d/1LKKTUd1lOS3jOqgDaPekJ7bWn-2uXCYZ/view?usp=drivesdk</identifier>
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