01316nam a2200289Ia 4500 MX-MdCICY 20260521091258.0 CICY B-11867 Application of Polyhydroxyalkanoates Nanoparticles as Intracellular Sustained Drug-Release Vectors Journal of BioMaterials Science, 21(1), p.127-140, 2010 Polyhydroxybutyrate (PHB), co-polyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx), and polylactic acid (PLA)were used to prepare nanoparticles with average sizes of 160, 250 and 150 nm, respectively. A lipid-soluble colorant, rhodamine B isothiocyanate (RBITC), was employed to study drug-release behaviors from these nanoparticles. A high RBITC drug-loading efficiency of over 75 POLYHYDROXYALKANOATES PHB NANOPARTICLES DRUG DELIVERY SUSTAINED RELEASE INTRACELLULAR DRUG RELEASE MACROPHAGE Xiong, Y. Yao, Y. Zhan, X. Chen, G. https://drive.google.com/file/d/1LKKTUd1lOS3jOqgDaPekJ7bWn-2uXCYZ/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 22021 22021 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-11867 2025-06-25 14:06:59 2025-06-25 REF1