01825nam a2200229Ia 4500 MX-MdCICY 20260521091252.0 CICY B-11661 Identification of MicroRNAs Involved in Pathogen-Associated Molecular Pattern-Triggered Plant Innate Immunity1[W] Plant Physiology, 152, p.2222-2231, 2010 Pathogen-associated molecular patterns (PAMPs)trigger plant defenses when perceived by surface-localized immune receptors. PAMP-triggered immunity (PTI)plays a vital role in the resistance of plants to numerous potential pathogens. MicroRNA (miRNA)biogenesis is known to be important for PTI, but miRNA species involved in this process have not been fully explored. Here we show that the Arabidopsis (Arabidopsis thaliana)miRNA effector protein, Argonaute1 (AGO1), is required for a number of PTI responses including PAMP-induced callose deposition, gene expression, and seedling growth inhibition. Deep sequencing of AGO1-bound small RNAs led to the identification of a number of miRNAs that are up- or down-regulated by flg22, a well-studied PAMP. Overexpression of selected miRNAs in stable transgenic plants demonstrated that miR160a positively regulate PAMP-induced callose deposition, whereas miR398b and miR773 negatively regulate PAMPinduced callose deposition and disease resistance to bacteria, suggesting a complexity of the miRNA egulation in plant innate immunity. Li, Y. Zhang, Q. Zhang, J. Wu, L. Qi, Y. Zhou, J. https://drive.google.com/file/d/1MxGLRfhegLqjcTsqq5WHI8tQ9RXPsWx6/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 21816 21816 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-11661 2025-06-25 14:06:54 2025-06-25 REF1