01850nam a2200265Ia 4500003001000000005001700010040000900027090001200036245009600048490005100144520089300195650001701088650002001105650001501125650002401140650002201164650002401186700002501210700001801235856015601253942001401409008004101423999001701464952010301481MX-MdCICY20260521091223.0  cCICY  aB-1076710aPKS Activities and Biosynthesis of Cannabinoids and Flavonoids in Cannabis sativa L. Plants0 vPlant & Cell Physiology, 49, p.1767-1782, 20083 aPolyketide synthase (PKS)enzymatic activities were analyzed in crude protein extracts from cannabis plant tissues. Chalcone synthase (CHS, EC 2.3.1.74), stilbene synthase (STS, EC 2.3.1.95), phlorisovalerophenone synthase (VPS, EC 2.3.1.156), isobutyrophenone synthase (BUS)and olivetol synthase activities were detected during the development and growth of glandular trichomes on bracts. Cannabinoid biosynthesis and accumulation take place in these glandular trichomes. In the biosynthesis of the first precursor of cannabinoids, olivetolic acid, a PKS could be involved; however, no activity for an olivetolic acid-forming PKS was detected. Content analyses of cannabinoids and flavonoids, two secondary metabolites present in this plant, from plant tissues revealed differences in their distribution, suggesting a diverse regulatory control for these biosynthetic fluxes in the plant.14aCANNABINOIDS14aCANNABIS SATIVA14aFLAVONOIDS14aGLANDULAR TRICHOMES14aOLIVETOL SYNTHASE14aPOLYKETIDE SYNTHASE12aFlores-Sanchez, I.J.12aVerpoorte, R.40uhttps://drive.google.com/file/d/1sj17gf2ZEMPcH-M8VQ1m78oov1YcZ_vL/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx  2LoccREF1250602s9999    xx |||||s2   |||| ||und|d  c20938d20938  00102Loc40708F1aCICYbCICYcREd2025-06-25l0oB-10767r2025-06-25 14:06:37w2025-06-25yREF1