01735nam a2200253Ia 4500 MX-MdCICY 20260521091223.0 CICY B-10767 PKS Activities and Biosynthesis of Cannabinoids and Flavonoids in Cannabis sativa L. Plants Plant & Cell Physiology, 49, p.1767-1782, 2008 Polyketide synthase (PKS)enzymatic activities were analyzed in crude protein extracts from cannabis plant tissues. Chalcone synthase (CHS, EC 2.3.1.74), stilbene synthase (STS, EC 2.3.1.95), phlorisovalerophenone synthase (VPS, EC 2.3.1.156), isobutyrophenone synthase (BUS)and olivetol synthase activities were detected during the development and growth of glandular trichomes on bracts. Cannabinoid biosynthesis and accumulation take place in these glandular trichomes. In the biosynthesis of the first precursor of cannabinoids, olivetolic acid, a PKS could be involved; however, no activity for an olivetolic acid-forming PKS was detected. Content analyses of cannabinoids and flavonoids, two secondary metabolites present in this plant, from plant tissues revealed differences in their distribution, suggesting a diverse regulatory control for these biosynthetic fluxes in the plant. CANNABINOIDS CANNABIS SATIVA FLAVONOIDS GLANDULAR TRICHOMES OLIVETOL SYNTHASE POLYKETIDE SYNTHASE Flores-Sanchez, I.J. Verpoorte, R. https://drive.google.com/file/d/1sj17gf2ZEMPcH-M8VQ1m78oov1YcZ_vL/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 20938 20938 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-10767 2025-06-25 14:06:37 2025-06-25 REF1