02105nam a2200313Ia 4500 MX-MdCICY 20260521091105.0 CICY B-8212 Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American trypanosomes of 13 native plants Journal of EthnoPharmacology, 62(3), p.195-202, 1998 Extracts were prepared from 13 native plants used for the treatment of protozoal infections. Activity against bacteria and fungi was demonstrated by dilution procedures; Trypanosoma cruzi was evaluated in vitro against epimastigote and trypomastigotes and in vivo against trypomastigotes. In active extracts, toxicity was evaluated by Artemia salina nauplii, oral acute toxicity (1-5 g:kg)and oral and intraperitoneal subacute toxicity in mice (500 mg:kg). From the plants screened, six showed activity (02 mg:ml)against bacteria, three against yeasts, five against Microsporum gypseum and five against T. cruzi in vitro and:or in vivo. In vitro and in vivo activity was demonstrated by Neurolaena lobata and Solanum americanum; in vitro or in vivo activity was shown by Acalypha guatemalensis, Peti6eria alliacea and Tridax procumbens. Toxicity studies showed that extracts from S. americanum are toxic to A. salina (aqueous, 160 ppm). None showed acute or oral toxicity to mice; S. americanum showed intraperitoneal subacute toxicity. GUATEMALA ANTITRYPANOSOME ACTIVITY ANTIBACTERIAL ACTIVITY ANTIFUNGAL ACTIVITY ACALYPHA GUATEMALENSIS NEUROLAENA LOBATA SOLANUM AMERICANUM Caceres, A. López, B. González, S. Berger, I. Tada, I. Maki, J. https://drive.google.com/file/d/1FMv_UgjMF9JA3NU84zb_C4UcuCzN9sp5/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 18457 18457 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-8212 2025-06-25 12:47:16 2025-06-25 REF1