02029nam a2200277Ia 4500003001000000005001700010040000900027245016200036490005700198520104100255650001401296650002901310650002701339650002401366650002701390650002201417650002301439700001601462700001601478700001901494700001501513700001301528700001301541856015601554008004101710MX-MdCICY20260521091105.0  cCICY10aPlants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American trypanosomes of 13 native plants0 vJournal of EthnoPharmacology, 62(3), p.195-202, 19983 aExtracts were prepared from 13 native plants used for the treatment of protozoal infections. Activity against bacteria and fungi was demonstrated by dilution procedures; Trypanosoma cruzi was evaluated in vitro against epimastigote and trypomastigotes and in vivo against trypomastigotes. In active extracts, toxicity was evaluated by Artemia salina nauplii, oral acute toxicity (1-5 g:kg)and oral and intraperitoneal subacute toxicity in mice (500 mg:kg). From the plants screened, six showed activity (02 mg:ml)against bacteria, three against yeasts, five against Microsporum gypseum and five against T. cruzi in vitro and:or in vivo. In vitro and in vivo activity was demonstrated by Neurolaena lobata and Solanum americanum; in vitro or in vivo activity was shown by Acalypha guatemalensis, Peti6eria alliacea and Tridax procumbens. Toxicity studies showed that extracts from S. americanum are toxic to A. salina (aqueous, 160 ppm). None showed acute or oral toxicity to mice; S. americanum showed intraperitoneal subacute toxicity.14aGUATEMALA14aANTITRYPANOSOME ACTIVITY14aANTIBACTERIAL ACTIVITY14aANTIFUNGAL ACTIVITY14aACALYPHA GUATEMALENSIS14aNEUROLAENA LOBATA14aSOLANUM AMERICANUM12aCaceres, A.12aLópez, B.12aGonzález, S.12aBerger, I.12aTada, I.12aMaki, J.40uhttps://drive.google.com/file/d/1FMv_UgjMF9JA3NU84zb_C4UcuCzN9sp5/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d