02116nam a2200313Ia 4500003001000000005001700010040000900027090001100036245007800047490005600125520107400181650001701255650001701272650001501289650002301304650001601327650001701343650001901360650001201379650003101391700002101422700001401443700001501457856015601472942001401628008004101642999001701683952010201700MX-MdCICY20260521091035.0  cCICY  aB-725010aFeatures and functions of covalently linked proteins in fungal cell walls0 vFungal Genetics and Biology, 42(8), p.657-675, 20053 aThe cell walls of many ascomycetous yeasts consist of an internal network of stress-bearing polysaccharides, which serve as a scaVold for a dense external layer of glycoproteins. GPI-modiWed proteins are the most abundant cell wall proteins and often display a common organization. Their C-terminus can link them covalently to the polysaccharide network, they possess an internal serineand threonine-rich spacer domain, and the N-terminal region contains a functional domain. Other proteins bind to the polysaccharide network through a mild-alkali-sensitive linkage. Many cell wall proteins are carbohydrate/glycan-modifying enzymes; adhesion proteins are prominent; proteins involved in iron uptake are present, and also specialized proteins that probably help the fungus to survive in its natural environment. The protein composition of the cell wall depends on environmental conditions and developmental stage. We present evidence that the cell wall of mycelial species of the Ascomycotina is similarly organized and contains glycoproteins with comparable functions.14aGPI-PROTEINS14aPIR-PROTEINS14aPROTEOMICS14aCELL WALL POROSITY14aIRON UPTAKE14aANTIGENICITY14aHYDROPHOBICITY14aBIOWLMS14aHOST-PATHOGEN INTERACTIONS12aDe Groot, P.W.J.12aRam, A.F.12aKlis, F.M.40uhttps://drive.google.com/file/d/1QpOfe7TG3T0ymSK1tdl_zqREWcPW2swd/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx  2LoccREF1250602s9999    xx |||||s2   |||| ||und|d  c17520d17520  00102Loc40708F1aCICYbCICYcREd2025-06-25l0oB-7250r2025-06-25 12:46:57w2025-06-25yREF1