02002nam a2200301Ia 4500 MX-MdCICY 20260521091035.0 CICY B-7250 Features and functions of covalently linked proteins in fungal cell walls Fungal Genetics and Biology, 42(8), p.657-675, 2005 The cell walls of many ascomycetous yeasts consist of an internal network of stress-bearing polysaccharides, which serve as a scaVold for a dense external layer of glycoproteins. GPI-modiWed proteins are the most abundant cell wall proteins and often display a common organization. Their C-terminus can link them covalently to the polysaccharide network, they possess an internal serineand threonine-rich spacer domain, and the N-terminal region contains a functional domain. Other proteins bind to the polysaccharide network through a mild-alkali-sensitive linkage. Many cell wall proteins are carbohydrate/glycan-modifying enzymes; adhesion proteins are prominent; proteins involved in iron uptake are present, and also specialized proteins that probably help the fungus to survive in its natural environment. The protein composition of the cell wall depends on environmental conditions and developmental stage. We present evidence that the cell wall of mycelial species of the Ascomycotina is similarly organized and contains glycoproteins with comparable functions. GPI-PROTEINS PIR-PROTEINS PROTEOMICS CELL WALL POROSITY IRON UPTAKE ANTIGENICITY HYDROPHOBICITY BIOWLMS HOST-PATHOGEN INTERACTIONS De Groot, P.W.J. Ram, A.F. Klis, F.M. https://drive.google.com/file/d/1QpOfe7TG3T0ymSK1tdl_zqREWcPW2swd/view?usp=drivesdk Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx Loc REF1 250602s9999 xx |||||s2 |||| ||und|d 17520 17520 0 0 Loc 0 0 F1 CICY CICY RE 2025-06-25 0 B-7250 2025-06-25 12:46:57 2025-06-25 REF1