01560nam a2200193Ia 4500003001000000005001700010040000900027245010800036490006000144520086000204650001901064650002101083650001301104650001601117700002001133700001601153856015601169008004101325MX-MdCICY20260521091019.0  cCICY10aPurine alkaloid producing cell cultures: fundamental aspects and possible applications in biotechnology0 vEnzyme and Microbial Technology , 9(8), p.450-458, 19873 aCoffea arabica is one of the plant species that has been widely studied with attention largely being given to its secondary products, caffeine and other purine alkaloids. The biosynthesis and significance of these alkaloids for the plant are elucidated and presented. Tissue cell culture and fundamental aspects of cell growth and alkaloid productivity are also discussed. The feasibility of Coffea cultivation in cell suspension has recently attracted the interest of many researchers. Although this cultivation is not of commercial interest, Coffea is especially suitable as a model cell line for reaction engineering studies because the purine alkaloids are well-characterised and readily released in culture medium. The use of free and immobilized coffee cells in various types of bioreactors (stirred tank, expanded bed, and membrane device)is shown.14aCOFFEA ARABICA14aPURINE ALKALOIDS14aCAFFEINE14aBIOREACTORS12aPrenosil, J. E.12aHegglin, M.40uhttps://drive.google.com/file/d/1v4MzjMH7nl8-zR0bGN7eW3spQvFYeo-M/view?usp=drivesdkzPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx250602s9999    xx |||||s2   |||| ||und|d