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In vitro anti-Helicobacter pylori activity of Syzygium aromaticum and the preliminary mechanism of action

Material type: TextSeries: ; Journal of EthnoPharmacology, 288, p.114995, 2022Contained works:
  • Peng, C
  • Sang, S
  • Shen, X
  • Zhang, W
  • Yan, J
  • Chen, P
  • Yao, M
Subject(s): Online resources: Abstract: Ethnopharmacological relevance: The dried flower bud of Syzygium aromaticum (L.)Merr. & L.M Perry (S. aromaticum)(Myrtaceae), also known as clove, was used in Traditional Chinese Medicine (TCM)to aid gastrointestinal function and treat stomach disorders including vomiting, flatulence and nausea. And it is a food homology medicine which is a promising candidate for H. pylori treatment. H. pylori is a Gram-negative bacterium that infects approximately 50 percent of the human population worldwide, which is closely related to multiple gastric diseases, including gastric cancer. However, there are still no sufficient studies on the anti-H. pylori activity of S. aromaticum, especially for the mechanism of action.
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Ethnopharmacological relevance: The dried flower bud of Syzygium aromaticum (L.)Merr. & L.M Perry (S. aromaticum)(Myrtaceae), also known as clove, was used in Traditional Chinese Medicine (TCM)to aid gastrointestinal function and treat stomach disorders including vomiting, flatulence and nausea. And it is a food homology medicine which is a promising candidate for H. pylori treatment. H. pylori is a Gram-negative bacterium that infects approximately 50 percent of the human population worldwide, which is closely related to multiple gastric diseases, including gastric cancer. However, there are still no sufficient studies on the anti-H. pylori activity of S. aromaticum, especially for the mechanism of action.

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